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Results for "

Src homology phosphatase 2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Phosphatase (192) PTEN (4) SHP2 (18) Src (96) 5-HT Receptor (3) Adrenergic Receptor (1) Akt (11) Aldose Reductase (1) Amyloid-β (1) Androgen Receptor (1) Antibiotic (22) Apoptosis (70) ATM/ATR (3) Aurora Kinase (3) Autophagy (19) Bacterial (15) Bcr-Abl (18) BCRP (1) Beta-secretase (1) Biochemical Assay Reagents (9) Btk (2) c-Fms (1) c-Kit (6) c-Met/HGFR (3) c-Myc (1) Calcineurin (3) CaMK (3) Carbonic Anhydrase (1) CDK (1) Cholinesterase (ChE) (3) Complement System (2) COX (3) CRISPR/Cas9 (3) Cytochrome P450 (3) DNA-PK (2) DNA/RNA Synthesis (4) Dopamine β-hydroxylase (1) Drug Metabolite (4) EBV (1) EGFR (10) Endogenous Metabolite (15) Epigenetic Reader Domain (1) Epoxide Hydrolase (1) ERK (5) Estrogen Receptor/ERR (1) FAK (4) FGFR (12) FKBP (3) FLT3 (3) Fluorescent Dye (9) Formyl Peptide Receptor (FPR) (1) Fungal (7) FXR (1) G-quadruplex (3) Gap Junction Protein (1) GCGR (1) Glucosidase (2) Glutaminase (1) Histone Methyltransferase (2) HIV (2) HSP (2) HSV (1) IAP (1) IGF-1R (1) iGluR (3) IKK (1) Influenza Virus (1) Integrin (2) Isotope-Labeled Compounds (7) JAK (8) JNK (2) Leukotriene Receptor (1) LIM Kinase (LIMK) (1) LXR (1) MAP3K (2) MAPKAPK2 (MK2) (2) MEK (1) Microtubule/Tubulin (4) MMP (2) MNK (1) Molecular Glues (1) Monoamine Oxidase (2) mTOR (2) Necroptosis (1) Neuropeptide Y Receptor (1) NF-κB (3) NO Synthase (1) Notch (1) Nuclear Factor of activated T Cells (NFAT) (1) p38 MAPK (5) PAK (1) Parasite (17) PDGFR (14) PERK (1) Phosphodiesterase (PDE) (2) Phospholipase (1) PI3K (6) PKA (2) PKC (5) PKD (1) Polo-like Kinase (PLK) (1) Progesterone Receptor (1) Prostaglandin Receptor (1) PROTACs (3) Protease Activated Receptor (PAR) (1) Pyk2 (1) Raf (7) Ras (3) Reactive Oxygen Species (6) RET (3) Reverse Transcriptase (2) Ribosomal S6 Kinase (RSK) (3) ROR (1) SARS-CoV (2) Secretin Receptor (1) Ser/Thr Protease (2) Sirtuin (2) Small Interfering RNA (siRNA) (3) STAT (9) Syk (3) Thyroid Hormone Receptor (1) Tie (1) Topoisomerase (3) VEGFR (15) Wnt (1)
By Research Areas:	Cancer (254) Cardiovascular Disease (11) Endocrinology (13) Infection (36) Inflammation/Immunology (58) Metabolic Disease (66) Neurological Disease (35)
Click Chemistry:	Alkynes (3)

477

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

118

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

NSC45586 sodium	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 sodium is an inhibitor of *pleckstrin homology* domain and leucine-rich repeat protein phosphatase (PHLPP)*. NSC45586 sodium targets the PP2C phosphatase* domain in PHLPP1 and PHLPP2. NSC45586 sodium can activate AKT in neurons .

SRC-3-IN-2	Others	Cancer
SRC-3-IN-2 (SI-12 6c)is an orally active steroid receptor coactivator 3 (SRC-3) inhibitor. SRC-3-IN-2 has antitumor activity .

Sydowimide A	Phosphatase	Inflammation/Immunology
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

NSC45586	Akt Ser/Thr Protease	Neurological Disease Cancer
NSC45586 is an inhibitor of *pleckstrin homology* domain and leucine-rich repeat protein phosphatase (PHLPP)*. NSC45586 targets the PP2C phosphatase* domain in PHLPP1 and PHLPP2. NSC45586 can activate AKT in neurons .

Phosphatase Binder-1	Others	Cancer
Phosphatase Binder-1 (comppund i-196) provides bifunctional compounds that efficiently dephosphorylate certain phospho-activated target proteins. Phosphatase Binder-1 plays an important role in cancer .

*Alkaline phosphatase, Bovine intestine* 1 Publications Verification Apase	Endogenous Metabolite	Metabolic Disease Cancer
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation ^[2].

Tetramethylcurcumin FLLL31	STAT Apoptosis	Inflammation/Immunology Cancer
Tetramethylcurcumin (FLLL31), derived from curcumin, specifically suppresses the phosphorylation of STAT3 by binding selectively to Janus kinase 2 and the STAT3 Src homology-2 domain. Tetramethylcurcumin exhibits anti-inflammatory and anti-cancer effects ^[2].

*KB SRC* 4**	Src	Cancer
KB SRC 4 is a potent, and highly selective *c-Src* inhibitor, with a K_i of 44 nM and a K_d of 86 nM, and shows no inhibition on c-Abl up to 125 μM; KB SRC 4 has antitumor activity.

Src Inhibitor 1 5+ Cited Publications Src Kinase Inhibitor 1; Src-l1	Src	Cancer
Src Inhibitor 1 is a potent, ATP-competitive and selective dual site *Src* tyrosine kinase inhibitor with IC₅₀ values of 44 nM for Src and 88nM for Lck.

RR-SRC
RR-SRC is a substrate for src-tyrosine-specific protein kinase .

SMAP-2 DT-1154	Phosphatase	Cancer
SMAP-2 (DT-1154) is an orally active protein phosphatase 2A (PP2A) activator, with anti-cancer activity ^[2].

Src Inhibitor 3 1 Publications Verification	Src	Inflammation/Immunology Cancer
Src Inhibitor 3 is a potent, orally active *c-terminal Src* kinase (CSK) with IC₅₀** values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. Src Inhibitor 3 shows the ability to increase T cell proliferation induced by T cell receptor signaling .

JC-010a	SHP2 Apoptosis	Cancer
JC-010a is a selective *SHP2* allosteric inhibitor. JC-010a inhibits cancer cells proliferation. JC-010a can be used for the research of cancer .

Ethoxysanguinarine 1 Publications Verification	Apoptosis	Cancer
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth .

*T338C Src-IN-1*
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).

*p60c-src* substrate II**	Src	Cancer
p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase *pp60c-src* .

Phosphatase-IN-1	Phosphatase Fungal	Infection
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a *phosphatidate phosphatase* (Pah)** inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads .

SRC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SRC Human Pre-designed siRNA Set A contains three designed siRNAs for SRC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Src Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Src Mouse Pre-designed siRNA Set A contains three designed siRNAs for Src gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Src Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Src Rat Pre-designed siRNA Set A contains three designed siRNAs for Src gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

WH-4-023 4 Publications Verification Dual LCK/Src inhibitor	Src	Cancer
WH-4-023 is a potent and selective dual *Lck/Src* inhibitor with IC₅₀ of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.

EPQpYEEIPIYL 1 Publications Verification	Src	Cancer
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains ^[2].

*Acid phosphatase, wheat* ACP	Endogenous Metabolite	Metabolic Disease
Acid phosphatase, wheat (ACP) is an enzyme that removes phosphate from other molecules during digestion. Acid phosphatase catalyzes the conversion of orthophosphoric monoester and H2O to alcohol and phosphoric acid .

*pp60 (v-SRC) Autophosphorylation Site, Phosphorylated*	EGFR	Others
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .

Thymolphthalein monophosphate disodium hydrate	Phosphatase	Others
Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum ^[2].

*T338C Src-IN-2*
T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.

4-Methylsalicylic acid	IAP	Inflammation/Immunology
4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor .

SHP1-IN-1	Phosphatase Fluorescent Dye	Cancer
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe ³⁺ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .

CPDA	Phosphatase	Metabolic Disease
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor.

TRC-766	Phosphatase	Others
TRC-766 is a negative control of RTC-5 (TRC-382). TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase .

Fast Red Violet LB	Fluorescent Dye	Others
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining ^[2].

Calyculin A 10+ Cited Publications (-)-Calyculin A	Phosphatase	Cancer
Calyculin A ((-)-Calyculin A) is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC₅₀s of 2 nM and 0.5-1 nM, respectively .

Fast Red Violet LB Zinc chloride	Fluorescent Dye	Others
Fast Red Violet LB Zinc chloride is a stain that stains tartrate-resistant acid phosphatase (TRAP) and Fast Red Violet LB Zinc chloride can be used to stain alkaline phosphatase (ALP) activity ^[2].

(Rac)-LB-100	Others	Cancer
(Rac)-LB-100 is the racemate of LB-100. LB-100 is a protein phosphatase 2A (PP2A) inhibitor .

CGP77675	Src	Cancer
CGP77675 is an orally active and potent inhibitor of *Src* family kinases. CGP77675 inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src (IC₅₀s of 5-20 and 40 nM, respectively), and also inhibits Src, EGFR, KDR, v-Abl, and Lck with IC₅₀s of 5-20, 40, 20, 150, 1000, 310, and 290 nM, respectively. Anticancer activity .

CGP77675 hydrate	Src	Cancer
CGP77675 hydrate is an orally active and potent inhibitor of *Src* family kinases. CGP77675 hydrate inhibits phosphorylation of peptide substrates and autophosphorylation of purified Src (IC₅₀s of 5-20 and 40 nM, respectively),and also inhibits Src, EGFR, KDR, v-Abl, and Lck with IC₅₀s of 0.02, 0.15, 1.0, 0.31, and 0.29 μM, respectively. Anticancer activity .

Pyridostatin hydrochloride 15+ Cited Publications RR82 hydrochloride	G-quadruplex	Cancer
Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent (K_d=490 nM). Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells ^[2].

Pyridostatin RR82	G-quadruplex	Cancer
Pyridostatin (RR82) is a G-quadruplex DNA stabilizing agent (K_d=490 nM). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets the proto-oncogene Src. Pyridostatin reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells ^[2].

Dibefurin	Phosphatase Endogenous Metabolite	Others
Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase .

DGY-06-116 1 Publications Verification	Src	Cancer
DGY-06-116 is an irreversible covalent, selective *Src* inhibitor with an IC₅₀ of 3nM. DGY-06-116 inhibits FGFR1 with an IC₅₀ of 8340 nM .

DT-061 5+ Cited Publications	Phosphatase	Cancer
DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis .

Pyridostatin TFA RR82 TFA	G-quadruplex	Cancer
Pyridostatin (RR82) TFA is a G-quadruplex DNA stabilizing agent (K_d=490 nM). Pyridostatin TFA promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin TFA targets the proto-oncogene Src. Pyridostatin TFA reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells ^[2] .

FPA-124	Akt Apoptosis	Cancer
FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC₅₀ of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis ^[2].

Cyclosporin A Maximum Cited Publications 97 Publications Verification Cyclosporine A; Ciclosporin A; CsA	Molecular Glues Phosphatase Complement System Antibiotic	Inflammation/Immunology Cancer
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

DiFMUP 6,8-Difluoro-4-methylumbelliferyl phosphate	Phosphatase	Others
DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader ^[2].

Fenvalerate
Fenvalerate is a potent *protein phosphatase 2B (calcineurin)* inhibitor with an IC₅₀ of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .

Cat. No.	Product Name

HY-L081

Phosphatase Inhibitor Library

132 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 132 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

HY-L055

Medicine Food Homology Compound Library

1709 compounds

Medicine Food Homology (MFH) means that some food themselves are medicines and there is no absolute boundary between them. MFH theory combines the function of food and medicine together scientifically and MFH materials can be used both for food and medicine. Besides nutritional value, MFH materials also have the functions in the prevention and treatment of disease and many other healthcare effects. Food as medicines has many benefits because of their safety while taking drugs will bring inevitable side effect to people. In order to ensure the safe use of functional food, National Health Commission of People's Republic of China made specific provisions on MFH items. More than 100 kinds of widely used MFH materials have been released.

Based on MFH items released by National Health Commission, PRC, MCE carefully designs a unique collection of 1709 Medicine Food Homology Compounds with high safety that can be used for high throughput and high content screening for drug discovery.

Cat. No.	Product Name	Type

HY-D1676

Thymolphthalein monophosphate disodium hydrate

Fluorescent Dyes/Probes

Thymolphthalein monophosphate disodium hydrate is a chromogenic substrate for the determination of acid phosphatase and alkaline phosphatase. Thymolphthalein is released during the reaction, increases the pH of the medium for easy detection, produces color and stops hydrolysis. Thymolphthalein monophosphate disodium hydrate can be used for the specific detection of prostatic phosphatase in serum ^[2].

HY-D2204

SHP1-IN-1	Fluorescent Dyes/Probes
SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe ³⁺ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM) .

HY-D1491

Fast Red Violet LB	Dyes
Fast Red Violet LB is a dye for staining tartrate resistant acid phosphatase (TRAP). Fast Red Violet LB can be used for alkaline phosphatase (ALP) activity staining ^[2].

HY-D1739

DDAO phosphate diammonium	Fluorescent Dyes/Probes
DDAO phosphate diammonium is a fluorescent phosphatase substrate. DDAO phosphate diammonium has tunable excitation wavelength (600-650nm) and long emission wavelength (λem=656nm). DDAO phosphate diammonium can be used to detect the activity of different enzymes such as β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin and esterase.

HY-D1208

CDP-Star

Chromogenic Substrates

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

HY-D0994

4-Methylumbelliferyl phosphate 4-MUP; MUP	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline *phosphatase* fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant ^[2] .

HY-149835

TTX-P	Fluorescent Dyes/Probes
TTX-P is a fluorescent probe. TTX-P responds in situ to the overexpressed alkaline phosphatase (ALP) in liver, imaging of diabetic liver injury in the near-infrared second-window (NIR-II) region .

HY-15928

PNPP disodium 1 Publications Verification Para-nitrophenyl phosphate disodium	Chromogenic Substrates
PNPP (Para-nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

HY-15909

BCIP BCIP p-toluidine salt; X-phosphate p-toluidine salt	Chromogenic Substrates
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

HY-D1520

Naphthol AS-GR phosphate disodium	Fluorescent Dyes/Probes
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .

HY-D0994A

4-Methylumbelliferyl phosphate disodium 4-MUP disodium; MUP disodium	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline *phosphatase* fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant ^[2] .

HY-15925

Nitro blue tetrazolium chloride 4 Publications Verification NBT	Chromogenic Substrates
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .

HY-15764G

A 419259 (GMP) RK-20449 (GMP)	Fluorescent Dye
A 419259 GMP is the GMP grade A 419259 (HY-15764), inducing cell apoptosis. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. A 419259 (RK-20449) is a broad-spectrum pyrrole-pyrimidine inhibitor targeting Src, Lck, and Lyn with IC₅₀s of 9 nM, <3 nM, and <3 nM, respectively ^[2].

Cat. No.	Product Name	Type

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 2 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-D0852

Sodium orthovanadate 5 Publications Verification	Biochemical Assay Reagents
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-19695

(-)-p-Bromotetramisole oxalate 1 Publications Verification L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate	Biochemical Assay Reagents
(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

HY-D1208

CDP-Star

Chromogenic Substrates

CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .
HY-112832

Lumigen APS-5

Enzyme Substrates

Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

HY-P2844

Polynucleotide kinase	Biochemical Assay Reagents
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-15906

AMPPD

Lumi-Phos Plus; Lumigen PPD; PPD
Enzyme Substrates

AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

HY-130767

Naphthol AS-TR phosphate

Biochemical Assay Reagents

Naphthol AS-TR Phosphate is a water-soluble dye commonly used as an enzyme substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase to form a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-W045537

5-Bromo-4-chloro-1H-indol-3-yl phosphate sodium

Biochemical Assay Reagents

Sodium 5-bromo-4-chloro-1H-indol-3-yl phosphate is commonly used as a substrate for phosphatase assays in biochemistry and molecular biology. This compound is converted by phosphatases to a yellow compound that can be easily measured spectrophotometrically or fluorometrically. Furthermore, it has been used as a useful reagent in enzyme-catalyzed reactions and a tool for studying signal transduction pathways.

HY-15764G

A 419259 (GMP) RK-20449 (GMP)	Biochemical Assay Reagents
A 419259 GMP is the GMP grade A 419259 (HY-15764), inducing cell apoptosis. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. A 419259 (RK-20449) is a broad-spectrum pyrrole-pyrimidine inhibitor targeting Src, Lck, and Lyn with IC₅₀s of 9 nM, <3 nM, and <3 nM, respectively ^[2].

HY-W250153

Adenosine 3'-phosphate 5'-phosphosulfate lithium	Biochemical Assay Reagents
Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group ^[2].

HY-W250153A

Adenosine 3'-phosphate 5'-phosphosulfate lithium, hydrate	Biochemical Assay Reagents
Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group ^[2].

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate

2-Phospho-L-ascorbic acid magnesium hydrate

Biochemical Assay Reagents

L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation ^[2] .

HY-W745090

Isomaltulose monohydrate

Biochemical Assay Reagents

Isomaltulose monohydrate is a fMLP inhibitor and also inhibits Src kinase, ERK1/2, p38 and AKT phosphorylation signals in immune regulation. Isomaltulose monohydrate can interfere with the interaction between the βγ subunit of the fMLP receptor Gi protein and its downstream molecules, thereby inhibiting fMLP-induced respiratory burst. Isomaltulose monohydrate inhibits fMLP (0.1 μM)-induced superoxide anion production (IC₅₀: 1.98 μM) , cathepsin G release (IC< sub>50: 2.76 μM) and chemotaxis. Isomaltulose monohydrate can improve excessive activation of neutrophils and reduce inflammation or tissue damage. A series of derivatives of Isomaltulose monohydrate are found to have inhibitory effects on FSGS-related TRPC6 functional mutants .

Cat. No.	Product Name	Target	Research Area

HY-P2513

Src Optimal Peptide Substrate

Peptides Others

Src Optimal Peptide Substrate is a highly specific Src substrate. Src Optimal Peptide Substrate can used to measure the Src activity .
HY-P5464

SRC-1 NR box peptide

Peptides Others

SRC-1 NR box peptide is a biological active peptide. (This peptide is a 14-amino acid fragment from the steroid receptor cofactor SRC-1 NR II.)

HY-P5458

SRC-1 (686-700)	Peptides	Others
SRC-1 (686-700) is a biological active peptide. (This peptide is amino acids 686 to 700 fragment containing the second LXXLL motif, derived from NR box II of steroid receptor coactivator (SRC1). Coactivator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription.)

HY-P3743

*p60c-src* Substrate**	Peptides	Others
p60c-src Substrate is an efficient and specific substrate for *p60c-src* protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides ^[2].

HY-P3773

p60c-src substrate II

Src Cancer

p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src .

HY-P3744

*pp60v-src* Autophosphorylation site**	Peptides	Others
pp60v-src Autophosphorylation site is a synthetic peptide. pp60v-src Autophosphorylation site can be used for various biochemical studies .

HY-P2372

P60v-src(137-157)

Peptides Others

P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60 ^v-src (IC₅₀: 7.5 μM) ^[2].

HY-P3771

*p60c-src* substrate II, phosphorylated**	Peptides	Others
p60c-src substrate II, phosphorylated is a pentapeptide. p60c-src substrate II, phosphorylated is a p60c-src substrate II phosphorylated polypeptide. Protein phosphorylation is an important post-translationmodification of protein that is indispensible in biological regulations .

HY-P1199

*pp60 c-src* (521-533) (phosphorylated)**	Peptides	Others
pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527 .

HY-P3279

EPQpYEEIPIYL 1 Publications Verification	Src	Cancer
EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains ^[2].

HY-P2548

*pp60 (v-SRC) Autophosphorylation Site, Phosphorylated*	EGFR	Others
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .

HY-P3633

Locustatachykinin II Lom-TK II	Peptides	Neurological Disease
Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine .

HY-P2040

Nodularin

Peptides Cancer

Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .

HY-P5363

PAP 248–286 Prostatic Acid phosphatase(248-286)	HIV	Others
PAP 248–286 is a biological active peptide. (Prostatic Acid Phosphatase (248-286), PAP (248-286) peptide is a semen-derived enhancer of viral infection (SEVI) factor found in semen. This peptide greatly increases HIV infection through enhanced virion attachment to target cells.)

HY-P5996

MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2	Peptides	Others
MCA-Gly-Asp-Ala-Glu-pTyr-Ala-Ala-Lys(DNP)-Arg-NH2 is a protein tyrosine phosphatase fluorogenic substrate that can be detected at 393 nm (with excitation at 325 nm) .

HY-W141781

Cysteamine S-phosphate sodium Cystaphos sodium	Peptides	Metabolic Disease
Cysteamine S-phosphate (Cystaphos) sodium can be hydroIyzed to Cysteamine by human alkaline phosphatases. Cysteamine is an orally active agent for the research of nephropathic cystinosis and an antioxidant ^[2].

HY-P0320A

EGF Receptor Substrate 2 (Phospho-Tyr5) (TFA)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P0320B

EGF Receptor Substrate 2 (Phospho-Tyr5) (acetate)	Phosphatase Biochemical Assay Reagents	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P1247

Calcineurin autoinhibitory peptide	Phosphatase	Neurological Disease
Calcineurin autoinhibitory peptide is a selective inhibitor of *Ca ²⁺/calmodulin-dependent* protein phosphatase (calcineurin), with an IC₅₀** of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death ^[2].

HY-P1247A

Calcineurin autoinhibitory peptide TFA	Phosphatase	Neurological Disease
Calcineurin autoinhibitory peptide TFA is a selective inhibitor of *Ca ²⁺/calmodulin-dependent* protein phosphatase (calcineurin), with an IC₅₀** of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death ^[2].

HY-W007599

(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid	Peptides	Cancer
(S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid is a polypeptide derivative, can be used to synthesis multifunctional amphiphilic peptide dendrimer, as a nonviral gene vectors, realizes the method in cancer research. (S)-2,6-Bis((tert-butoxycarbonyl)amino)hexanoic acid also involves in the synthesis of an organic substance that increases the luminescence intensity of alkaline phosphatase substrates ^[2].

HY-P1183

Locustatachykinin I	Peptides	Neurological Disease Endocrinology
Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase ^[2].

HY-P0139

Gap 27 5 Publications Verification	Gap Junction Protein	Cardiovascular Disease
Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment ^[2].

HY-P1183A

Locustatachykinin I TFA	Peptides	Neurological Disease Endocrinology
Locustatachykinin I TFA is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I TFA exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I TFA is also a substrate for a deamidase ^[2].

HY-P2547

Tyrosine Kinase Peptide 1

Src Others

Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay .
HY-P5441

KRpTIRR

Peptides Others

KRpTIRR is a biological active peptide. (Phosphatase substrate.)
HY-P5447

RRLIEDAEpYAARG

Peptides Others

RRLIEDAEpYAARG is a biological active peptide. (Phosphatase substrate.)

HY-P5559

ND1-YL2	PROTACs	Cancer
ND1-YL2 is a PROTAC that selectively degrades *SRC-1* via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research .

HY-P1816

Fibronectin CS1 Peptide	Integrin	Cancer
The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models .

HY-P2844

Polynucleotide kinase	DNA/RNA Synthesis	Metabolic Disease
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-P6028

GSNKSKPK-NH2

Peptides Others

GSNKSKPK-NH2 is a model peptide based on a c-Src N-terminal peptide that can be used as NMT substrate .

HY-P5489

IGRP(206-214)	Peptides	Others
IGRP(206-214) is a biological active peptide. (This peptide corresponds to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice.)

HY-P6028A

GSNKSKPK-NH2 TFA

Peptides Others

GSNKSKPK-NH2 TFA is a model peptide based on a c-Src N-terminal peptide that can be used as NMT substrate .

HY-P3463

Beinaglutide GLP-1 (human)	GCGR	Metabolic Disease Inflammation/Immunology
Beinaglutide is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7–36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH) ^[2].

HY-P1200

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH	Src	Cancer
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC₅₀≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for **src SH3-SH2**:phosphoprotein interactions .

HY-P1200A

Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA	Src	Cancer
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC₅₀≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for **src SH3-SH2**:phosphoprotein interactions .

HY-P0217

Microcystin-RR Cyanoviridin RR	Phosphatase Apoptosis	Metabolic Disease
Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. Microcystin-RR induces Apoptosis and ER stress in mice liver ^[2].

HY-P1784

Secretin, canine	Secretin Receptor	Endocrinology
Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Secretin, canine can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway .

HY-P3677

Neuropeptide Y (2-36) (porcine)	Neuropeptide Y Receptor	Neurological Disease
Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC₅₀ values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders .

HY-P0219

Microcystin-LA	Phosphatase	Cancer
Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and *PP2A* with IC₅₀s of 0.3 and 0.3 nM, respectively .

HY-P4835

pTH (2-34) (human)	Peptides	Others
pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. pTH (2-34) is not as effective as pTH (1-34) .

HY-P0320

EGF Receptor Substrate 2 (Phospho-Tyr5)	Phosphatase	Others
EGF Receptor Substrate 2 (Phospho-Tyr5) acetate, a biologically active peptide, is a tyrosine phosphate substrate. EGF Receptor Substrate 2 (Phospho-Tyr5) acetate can be used to detect protein tyrosine phosphatases activity .

HY-P5387

Connexin mimetic peptide 40,37GAP26	Peptides	Others
Connexin mimetic peptide 40,37GAP26 is a biological active peptide. (This peptide corresponds to the GAP26 domain of the extracellular loop of the major vascular connexins (Cx37, Cx40), designated as 37, 40Gap 26 according to Cx homology. It was used to investigate the role of gap junctions in the spread of endothelial hyperpolarizations evoked by cyclopiazonic acid (CPA) through the wall of the rodent iliac artery. The gap junction plaques constructed from Cx37 and Cx40 were abundant in the endothelium. This peptide provides inhibitory effects against subintimal hyperpolarization.)

HY-P1039

R18 PHCVPRDLSWLDLEANMCLP	Raf	Cancer
R18 is a peptide antagonists of 14-3-3, with a K_D of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1 .

HY-P3940

Ac-MBP (4-14) Peptide	PKC	Others
Ac-MBP (4-14) Peptide is an acetylated MBP (4-14) peptide. MBP (4-14) Peptide is a very selective (protein kinase C) PKC substrate. Ac-MBP (4-14) Peptide can be used for PKC assay in extracts without prior purification to eliminate interfering protein kinases or phosphatases .

HY-P5438

Srctide	Peptides	Others
Srctide is a biological active peptide. (This is a peptide substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (KDR).)

HY-P5527F

FAM-CSKtide	Peptides	Others
FAM-CSKtide is a biological active peptide. (This is a FAM labeled peptide substrate (Abs/Em = 494/521 nm) for C-terminal Src kinase (Csk) and many other kinases such as Axl, cKit, ERBB4, Fes, Flt3, IGF-1 R, MET, MUSK, PYK2, Ret, TIE2, TrkA, VEGF-R1 and VEGF-R2.)

HY-P1039A

R18 TFA PHCVPRDLSWLDLEANMCLP TFA	Raf	Cancer
R18 TFA is a peptide antagonists of 14-3-3, with a K_D of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1 .

HY-P4823

pTH (1-37) (human)	Thyroid Hormone Receptor	Metabolic Disease
pTH (1-37) (human) is a fragment of parathyroid hormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis ^[2] .

HY-P3355

p-fin4	iGluR	Neurological Disease
p-fin4 is a peptide inhibitor of STEP Phosphatase-GluA2 AMPA receptor interaction with a Ki of 0.4 μM. p-fin4 restores the memory deficits and displays anxiolytic and antidepressant effects in a scopolamine-treated rat model. p-fin4 is a promising lead compound for novel cognitive enhancers and/or behavioral modulators .

Cat. No.	Product Name

HY-K0022

Phosphatase Inhibitor Cocktail II 315+ Cited Publications
Phosphatase Inhibitor Cocktail II effectively inhibits acid and alkaline phosphatases as well as protein tyrosine phosphatases(PTPs).

HY-K0021

Phosphatase Inhibitor Cocktail I Maximum Cited Publications 351 Publications Verification
Phosphatase Inhibitor Cocktail I effectively inhibits alkaline phosphatases and serine/threonine protein phosphatases such as PP1 and PP2A.

HY-K0023

Phosphatase Inhibitor Cocktail III

205+ Cited Publications

Phosphatase Inhibitor Cocktail III effectively inhibits serine/threonine and alkaline phosphatases.

HY-K0013

*Protease and Phosphatase* Inhibitor Cocktail (EDTA-Free, 10× in ddH2O)** 40+ Cited Publications
MCE Protease and Phosphatase Inhibitor Cocktail (EDTA-Free, 10× in ddH2O) protects protein from degradation by endogenous proteases released during protein extraction and purification.

Species:	Human (86) Virus (3) Mouse (23) Rat (4) Cynomolgus (1)
Tag:	GFP (1) His (95) SUMO (2) Tag Free (9) Avi (1) Myc (1) GST (16) MBP (1) Flag (3) Fc (7)
Source:	HEK293 (53) Sf9 insect cells (2) P. pastoris (3) Sf9 insect cells (23) E. coli (37)

Cat. No.	Compare	Product Name	Species	Source

HY-P700618

	SHP-2 Protein, Human (T253M, Q257L, His) protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433	Human	E. coli
	The SHP-2 protein is a key player downstream of the receptor and cytoplasmic protein tyrosine kinases, facilitating signal transduction from the cell surface to the nucleus. It actively regulates the MAPK pathway and dephosphorylates key substrates, including GAB1, ARHGAP35, EGFR, ROCK2 ("Tyr-722"), and CDC73. SHP-2 Protein, Human (T253M, Q257L, His) is the recombinant human-derived SHP-2 protein, expressed by E. coli , with N-6*His labeled tag and T253M, Q257L, , , mutation. The total length of SHP-2 Protein, Human (T253M, Q257L, His) is 592 a.a., with molecular weight of 70-75 kDa.

HY-P71854

	MINPP1 Protein, Human (P.pastoris, His) MINPP2; MIPP; Multiple inositol polyphosphate histidine phosphatase, 1; Multiple inositol polyphosphate phosphatase 1; multiple inositol polyphosphate phosphatase 2	Human	P. pastoris
	MINPP1 Protein, a dual-function phosphatase, regulates inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) levels through phosphoinositide 5- and phosphoinositide 6-phosphatase activity. It also acts as a 2,3-bisphosphoglycerate 3-phosphatase, crucial for bone development and chondrocyte transition. By controlling intracellular inositol polyphosphates, MINPP1 potentially influences cation homeostasis, impacting neural cell signaling through free cation availability. MINPP1 Protein, Human (P.pastoris, His) is the recombinant human-derived MINPP1 protein, expressed by P. pastoris, with N-His labeled tag. The total length of MINPP1 Protein, Human (P.pastoris, His) is 457 a.a., with molecular weight of ~55.3 kDa.

HY-P70937

	MINPP1 Protein, Human (HEK293, His) Multiple Inositol Polyphosphate phosphatase 1; 2,3-Bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; Inositol (1,3,4,5)-Tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase; MINPP1; MIPP	Human	HEK293
	MINPP1 Protein, a dual-function phosphatase, regulates inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) levels through phosphoinositide 5- and phosphoinositide 6-phosphatase activity. It also acts as a 2,3-bisphosphoglycerate 3-phosphatase, crucial for bone development and chondrocyte transition. By controlling intracellular inositol polyphosphates, MINPP1 potentially influences cation homeostasis, impacting neural cell signaling through free cation availability. MINPP1 Protein, Human (HEK293, His) is the recombinant human-derived MINPP1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of MINPP1 Protein, Human (HEK293, His) is 457 a.a., with molecular weight of ~56.0 kDa.

HY-P75979

	PPM1A Protein, Mouse (His) Protein phosphatase 1A; Protein phosphatase 2C Isoform Alpha; PP2C-Alpha; PPPM1A	Mouse	E. coli
	PPM1A is a multifunctional enzyme whose enzymatic activity exhibits broad specificity. It acts as a negative regulator of TGF-β signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export of SMAD, and termination of TGF-β-mediated signaling. PPM1A Protein, Mouse (His) is the recombinant mouse-derived PPM1A protein, expressed by E. coli , with C-His labeled tag. The total length of PPM1A Protein, Mouse (His) is 382 a.a., with molecular weight of ~44 kDa.

HY-P71227

	PPM1A Protein, Human (His) Protein phosphatase 1A; Protein phosphatase 2C Isoform Alpha; PP2C-Alpha; Protein phosphatase IA; PPM1A; PPPM1A	Human	E. coli
	PPM1A is a multifunctional enzyme that negatively regulates multiple signaling pathways. It significantly attenuates TGF-β signaling by dephosphorylating SMAD2 and SMAD3, leading to their dissociation from SMAD4, nuclear export, and signal termination. PPM1A Protein, Human (His) is the recombinant human-derived PPM1A protein, expressed by E. coli , with C-6*His labeled tag. The total length of PPM1A Protein, Human (His) is 381 a.a., with molecular weight of ~45.0 kDa.

HY-P701321

	SRC Protein, Human (His) Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-Src (p60-Src); Src1	Human	E. coli
	Src is a non-receptor protein tyrosine kinase that centralizes multiple cellular processes triggered by various receptors. It controls gene transcription, immune response, adhesion, cell cycle, apoptosis, migration and transformation. SRC Protein, Human (His) is the recombinant human-derived SRC protein, expressed by E. coli , with N-10*His labeled tag. The total length of SRC Protein, Human (His) is 535 a.a., with molecular weight of 64.2 kDa.

HY-P73422

	Src Protein, Human (sf9, His-GST) Proto-oncogene tyrosine-protein kinase Src; Src; p60-Src; Src1	Human	Sf9 insect cells
	Src is a non-receptor protein tyrosine kinase that centralizes multiple cellular processes triggered by various receptors. It controls gene transcription, immune response, adhesion, cell cycle, apoptosis, migration and transformation. Src Protein, Human (sf9, His-GST) is the recombinant human-derived Src protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Src Protein, Human (sf9, His-GST) is 536 a.a., with molecular weight of ~81 kDa.

HY-P73423

	Src Protein, Mouse (sf9, His-GST) Proto-oncogene tyrosine-protein kinase Src; Src; p60-Src; Src1	Mouse	Sf9 insect cells
	Src, a non-receptor protein tyrosine kinase, displays a unique ability to phosphorylate synaptophysin with high affinity. Src Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived Src protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Src Protein, Mouse (sf9, His-GST) is 535 a.a., with molecular weight of ~80 kDa.

HY-P702724

Src Protein, Human (sf9, His, Flag)

Proto-oncogene tyrosine-protein kinase Src; Src; p60-Src; Src1
Human Sf9 insect cells

HY-P71022

	PP1MG Protein, Human (His) Protein phosphatase 1G; Protein phosphatase 1C; Protein phosphatase 2C Isoform Gamma; PP2C-Gamma; Protein phosphatase Magnesium-Dependent 1 Gamma; PPM1G; PPM1C	Human	E. coli
	PP1MG Protein, a member of PPM family of serine/threonine phosphatases, has an important role in controlling cell cycle progression. PP1MG Proteinregulates the phosphorylation of SRSF3 in hepatocellular carcinoma (HCC) and contributes to the proliferation, invasion, and metastasis of HCC. PP1MG Protein forms a distinct holoenzyme complex with the PP2A regulatory subunit B56δ. B56δ‐PPM1G dephosphorylates α‐catenin at serine 641, which is necessary for the appropriate assembly of adherens junctions and the prevention of aberrant cell migration. PP1MG Protein, Human (His) is the recombinant human-derived PP1MG protein, expressed by E. coli , with C-6*His labeled tag. The total length of PP1MG Protein, Human (His) is 230 a.a., with molecular weight of ~30.0 kDa.

HY-P76759

	Calcineurin A/PPP3CA Protein, Human (sf9, His) Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; CALNA; CNA	Human	Sf9 insect cells
	Calcineurin A, also known as PPP3CA, is a calcium-dependent, calmodulin-stimulated protein phosphatase that plays a pivotal role in transducing intracellular Ca(2+)-mediated signals. Known substrates often contain a PxIxIT motif and/or an LxVP motif, highlighting the specificity of its phosphatase activity. In response to elevated Ca(2+) levels, Calcineurin A dephosphorylates and activates phosphatase SSH1, leading to cofilin dephosphorylation. Furthermore, upon increased Ca(2+) levels following mitochondrial depolarization, Calcineurin A dephosphorylates DNM1L, inducing its translocation to the mitochondrion. The protein also positively regulates CACNA1B/CAV2.2-mediated Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals. Calcineurin A dephosphorylates and activates transcription factor NFATC1, thereby regulating NFAT-mediated transcription by promoting nuclear translocation. Its broad array of functions includes the dephosphorylation of heat shock protein HSPB1, transcription factor ELK1, DARPP32, CRTC2, TFEB, and KLHL3, suggesting a crucial role in various cellular processes such as kidney development, secretion of salivary enzymes, bone formation, immune responses, and regulation of ion transport. The multifaceted roles of Calcineurin A underscore its significance in diverse cellular functions and signal transduction pathways. Calcineurin A/PPP3CA Protein, Human (sf9, His) is the recombinant human-derived Calcineurin A/PPP3CA protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of Calcineurin A/PPP3CA Protein, Human (sf9, His) is 520 a.a., with molecular weight of ~60 kDa.

HY-P76438

	ILKAP/PP2C delta Protein, Human (HEK293, His) Integrin-linked kinase-associated serine/threonine phosphatase 2C; ILKAP; PP2C delta	Human	HEK293
	The ILKAP/PP2C delta protein is a key phosphatase that potentially regulates cell cycle progression by dephosphorylating substrates essential for proliferation. It selectively binds to ILK and regulates cell adhesion and growth factor signaling. ILKAP/PP2C delta Protein, Human (HEK293, His) is the recombinant human-derived ILKAP/PP2C delta protein, expressed by HEK293 , with C-His labeled tag. The total length of ILKAP/PP2C delta Protein, Human (HEK293, His) is 392 a.a., with molecular weight of ~46 KDa.

HY-P71768

	*PLP phosphatase* Protein, Mouse (P.pastoris, His)** Pdxp; Cin; Plp; Plpp; Pyridoxal phosphate phosphatase; PLP phosphatase; Chronophin	Mouse	P. pastoris
	The PLP phosphatase protein plays a dual role as a pyridoxal phosphate (PLP) phosphatase and a protein serine phosphatase. Its enzymatic activity in vitamin B6 metabolism involves the dephosphorylation of PLP, PNP and PMP. PLP phosphatase Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived PLP phosphatase protein, expressed by P. pastoris , with N-His labeled tag. The total length of PLP phosphatase Protein, Mouse (P.pastoris, His) is 292 a.a., with molecular weight of ~33.5 kDa.

HY-P71150

	DUSP3 Protein, Human (His) Dual specificity protein phosphatase 3; DUSP3; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase; VHR	Human	E. coli
	DUSP3, a dual-specificity phosphatase, preferentially dephosphorylates phosphotyrosines. Its main function involves inactivating ERK1 and ERK2, thereby modulating associated cellular signaling pathways. DUSP3 Protein, Human (His) is the recombinant human-derived DUSP3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of DUSP3 Protein, Human (His) is 184 a.a., with molecular weight of 18-22 kDa.

HY-P7487

	*Alkaline Phosphatase/ALPP Protein, Human (HEK293, His)* rHuAlkaline phosphatase, His; ALPP; PLAP; ALP; AKP2; Alkaline phosphatase	Human	HEK293
	ALPP Protein, Human (HEK293, His) is a ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values.

HY-P70327A

	LMW-PTP/ACP1 Protein, Human (C-His) rHuLow molecular weight phosphotyrosine protein phosphatase/LMW-PTP, His; Low Molecular Weight Phosphotyrosine Protein phosphatase; LMW-PTP; LMW-PTPase; Adipocyte Acid phosphatase; Low Molecular Weight Cytosolic Acid phosphatase; Red Cell Acid phosphatase 1; ACP1	Human	E. coli
	LMW-PTP/ACP1, a phosphatase, acts on tyrosine phosphorylated proteins, low-molecular-weight aryl phosphates, and natural and synthetic acyl phosphates. Notably, there are substrate specificity differences between isoform 1 and isoform 2, with isoform 2 lacking phosphatase activity. LMW-PTP/ACP1 Protein, Human (C-His) is the recombinant human-derived LMW-PTP/ACP1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of LMW-PTP/ACP1 Protein, Human (C-His) is 157 a.a., with molecular weight of ~18.0 kDa.

HY-P7487A

	*Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His)* rHuAlkaline phosphatase, His; ALPP; PLAP; ALP; AKP2; Alkaline phosphatase	Human	HEK293
	Alkaline Phosphatase/ALPP Proteinas, an enzyme, effectively hydrolyzes various phosphate compounds. Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) is the recombinant human-derived Alkaline Phosphatase/ALPP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His) is 484 a.a., with molecular weight of approximately 62.5 kDa.

HY-P700950

	*Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His)* Alkaline phosphatase; Alkaline phosphatase, placental-like; EAP; Alpg; Akp5; Alppl2	Mouse	HEK293
	Alkaline Phosphatase/ALPG Proteinas, an enzyme, effectively hydrolyzes various phosphate compounds. Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Mouse (HEK293, His) is 484 a.a., with molecular weight of 55-70 kDa.

HY-P701947

	PR Protein, Human PPP2R3A; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha; PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B''-PR72/PR130; PP2A subunit B isoforms B72/B130; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B	Human	E. coli
	PR protein is the B regulatory subunit of PP2A, which regulates substrate selectivity, catalytic activity and directs enzyme localization. PP2A is a phosphatase complex consisting of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). PR Protein, Human is the recombinant human-derived PR protein, expressed by E. coli , with tag free. The total length of PR Protein, Human is 285 a.a., .

HY-P7880

	*Alkaline Phosphatase/ALPL Protein, Human (HEK293, His)* rHuAlkaline phosphatase, tissue-nonspecific isozyme/ALPL, His; Alkaline phosphatase; Tissue-Nonspecific Isozyme; AP-TNAP; TNSALP; Alkaline phosphatase Liver/Bone/Kidney Isozyme; ALPL	Human	HEK293
	Alkaline Phosphatase/ALPL Protein, Human (HEK 293, His) is a cell-surface homodimeric phosphohydrolase that is richly expressed in the skeleton, liver, kidney and developing teeth.

HY-P75813

	*glycoprotein/G Protein, HRSV (93% Homology, HEK293, His)* Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (93% homology)	Virus	HEK293
	The glycoprotein/G Protein, crucial in the immune response, forms the interleukin-31 receptor with OSMR. This receptor activates STAT3, and to a lesser extent, STAT1 and STAT5, playing a vital role in skin immunity and mediating IL31-induced itch, potentially involving TRPA1 and TRPV1. It positively regulates myeloid progenitor cell numbers and cycling status in the bone marrow, enhancing survival. Acting in viral infection, the glycoprotein/G Protein attaches the virion to the host cell membrane, interacts with heparan sulfate, modulates the immune response through CX3CR1, and aids in escaping antibody-dependent restriction by acting as an antigen decoy. glycoprotein/G Protein, HRSV (93% Homology, HEK293, His) is the recombinant Virus-derived glycoprotein/G protein, expressed by HEK293, with C-His labeled tag. The total length of glycoprotein/G Protein, HRSV (93% Homology, HEK293, His) is 232 a.a., with molecular weight of 60-90 kDa.

HY-P75814

	*Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His)* Human respiratory syncytial virus (RSV) (A, rsb1734) glycoprotein G / RSV-G Protein (95% homology)	Virus	HEK293
	A glycoprotein/G protein critical in the immune response forms the interleukin-31 receptor with OSMR. This receptor activates STAT3 and, to a lesser extent, STAT1 and STAT5, playing a critical role in skin immunity and mediating IL31-induced itch, possibly involving TRPA1 and TRPV1. Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His) is the recombinant Virus-derived Glycoprotein/G protein, expressed by HEK293 , with C-His labeled tag. The total length of Glycoprotein/G Protein, HRSV (95% Homology, HEK293, His) is 232 a.a., with molecular weight of ~50-100 kDa.

HY-P76713

	ACPL2 Protein, Human (HEK293, His) 2-phosphoxylose phosphatase 1; Acid phosphatase-like protein 2; PXYLP1; HEL124	Human	HEK293
	The ACPL2 protein plays a critical role in the regulation of glycosaminoglycan (GAG) chains by catalyzing the 2-O-dephosphorylation of xylose in proteoglycans. This step is critical for the synthesis of sulfated GAGs, including heparan sulfate and chondroitin sulfate. ACPL2 Protein, Human (HEK293, His) is the recombinant human-derived ACPL2 protein, expressed by HEK293 , with C-His labeled tag. The total length of ACPL2 Protein, Human (HEK293, His) is 480 a.a., with molecular weight of ~50 kDa.

HY-P700952

	*Alkaline Phosphatase/ALPG Protein, Human (HEK293, His)* Alkaline phosphatase; ALP-1; Alkaline phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2	Human	HEK293
	The Alkaline Phosphatase/ALPG protein, an enzyme, hydrolyzes phosphate compounds, breaking down various molecules. It acts as an alkaline phosphatase, cleaving phosphate esters and rendering molecules inactive. This versatile enzyme is vital in processes like bone mineralization, cellular signaling, and metabolism. Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) is the recombinant human-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Human (HEK293, His) is 484 a.a., with molecular weight of 58-68 kDa.

HY-P702581

Alkaline Phosphatase/ALPG Protein, Rat (HEK293, His)

Alkaline phosphatase; ALP-1; Alkaline phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2
Rat HEK293

HY-P72822

	ALPI Protein, Human (HEK293, His) Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, His) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-His labeled tag. The total length of ALPI Protein, Human (HEK293, His) is 484 a.a., with molecular weight of ~70-80 kDa.

HY-P72821

	ALPI Protein, Human (HEK293, Fc) Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, Fc) is the recombinant human-derived ALPI protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ALPI Protein, Human (HEK293, Fc) is 503 a.a., with molecular weight of 90-95 kDa.

HY-P74415

	*Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His)* Alkaline phosphatase; AP-TNAP; TNSALP; ALPL	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein is a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. ALPL is also a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. Mice that lack ALPL show symptoms of osteomalacia, softening of the bones. Moreover, ALPL stimulates mineralization mainly through modulation of the balance between inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) and also has a role in cardiovascular remodelling. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-His, C-8*His labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, His) is 502 a.a., with molecular weight of ~55 kDa.

HY-P74416

	*Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc)* Alkaline phosphatase; AP-TNAP; TNSALP; ALPL	Mouse	HEK293
	Alkaline Phosphatase/ALPL Protein is a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. ALPL is also a membrane-bound glycosylated enzyme that catalyzes the hydrolysis of phosphate esters at alkaline pH. Mice that lack ALPL show symptoms of osteomalacia, softening of the bones. Moreover, ALPL stimulates mineralization mainly through modulation of the balance between inorganic phosphate (Pi) and inorganic pyrophosphate (PPi) and also has a role in cardiovascular remodelling. Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Alkaline Phosphatase/ALPL protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Alkaline Phosphatase/ALPL Protein, Mouse (HEK293, Fc) is 502 a.a., with molecular weight of ~80.3 kDa.

HY-P700395

	ALPI Protein, Rat (HEK293, His) Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline phosphatase	Rat	HEK293
	The ALPI protein, an alkaline phosphatase enzyme, hydrolyzes phosphate compounds, demonstrating enzymatic activity in breaking down different phosphate molecules. ALPI Protein, Rat (HEK293, His) is the recombinant rat-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Rat (HEK293, His) is 491 a.a., with molecular weight of 55.9 kDa.

HY-P700949

	*Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His)* Alkaline phosphatase; PLAP-1; ALPP; PLAP	Cynomolgus	HEK293
	Alkaline Phosphatase (ALPP) is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. Zinc and magnesium are essential cofactors of ALPP. ALPP down-regulates the secretory activities of the intrahepatic biliary epithelium. Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Alkaline Phosphatase/ALPP protein, expressed by HEK293 , with C-His labeled tag. The total length of Alkaline Phosphatase/ALPP Protein, Cynomolgus (HEK293, His) is 483 a.a., with molecular weight of 57-67 kDa.

HY-P701948

	PR Protein, Human (His) PPP2R3A; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha; PP2A subunit B isoform PR72/PR130; PP2A subunit B isoform R3 isoform; PP2A subunit B isoforms B''-PR72/PR130; PP2A subunit B isoforms B72/B130; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B	Human	E. coli
	PR protein is the B regulatory subunit of PP2A, which regulates substrate selectivity, catalytic activity and directs enzyme localization. PP2A is a phosphatase complex consisting of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). PR Protein, Human (His) is the recombinant human-derived PR protein, expressed by E. coli , with N-6*His labeled tag. The total length of PR Protein, Human (His) is 285 a.a., .

HY-P71769

	PHPT1 Protein, Human (P.pastoris, His) 14kDa phosphohistidine phosphatase; CGI 202; HSPC141; Phosphohistidine phosphatase 1; PHP14	Human	P. pastoris
	The PHPT1 protein acts as a phosphohistidine phosphatase, catalyzing the dephosphorylation of phosphohistidine residues. This unique enzymatic activity makes PHPT1 a regulator of histidine phosphorylation events, suggesting that it is involved in signaling pathways or cellular processes that are critical for phosphohistidine modification. PHPT1 Protein, Human (P.pastoris, His) is the recombinant human-derived PHPT1 protein, expressed by P. pastoris , with N-His labeled tag. The total length of PHPT1 Protein, Human (P.pastoris, His) is 125 a.a., with molecular weight of ~15.8 kDa.

HY-P700394

	ALPI Protein, Human (HEK293, N-His) Intestinal-type alkaline phosphatase; IAP; ALPI; Alkaline phosphatase	Human	HEK293
	ALPI Proteinas, an alkaline phosphatase, effectively hydrolyzes diverse phosphate compounds. ALPI Protein, Human (HEK293, N-His) is the recombinant human-derived ALPI protein, expressed by HEK293, with N-10*His labeled tag. The total length of ALPI Protein, Human (HEK293, N-His) is 484 a.a., with molecular weight of 55.2 kDa.

HY-P700951

	*Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi)* Alkaline phosphatase; ALP-1; Alkaline phosphatase, placental-like; GCAP; PLAP-like; ALPG; ALPPL; ALPPL2	Human	HEK293
	The Alkaline Phosphatase/ALPG protein, an enzyme, hydrolyzes phosphate compounds, breaking down various molecules. It acts as an alkaline phosphatase, cleaving phosphate esters and rendering molecules inactive. This versatile enzyme is vital in processes like bone mineralization, cellular signaling, and metabolism. Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Alkaline Phosphatase/ALPG protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Alkaline Phosphatase/ALPG Protein, Human (Biotinylated, HEK293, His-Avi) is 484 a.a., with molecular weight of 56-70 kDa.

HY-P71241

	PSP Protein, Human (His) Phosphoserine phosphatase; PSP; PSPase; L-3-Phosphoserine phosphatase; O-Phosphoserine Phosphohydrolase; PSPH	Human	E. coli
	PSP protein catalyzes the final irreversible step in carbohydrate biosynthesis of L-serine through dephosphorylation of O-phospho-L-serine. PSP Protein, Human (His) is the recombinant human-derived PSP protein, expressed by E. coli , with C-6*His labeled tag. The total length of PSP Protein, Human (His) is 225 a.a., with molecular weight of 25-30 kDa.

HY-P74430

	*ACPP/Prostatic Acid Phosphatase* Protein, Mouse (HEK293, His)** ACP-3; ACPP; Prostatic Acid phosphatase; PAPf39; PAP	Mouse	HEK293
	The acid prostatic phosphatase (ACPP) protein, encapsulated in virus-like particles (VLPs), is an acid tyrosine phosphatase that skillfully dephosphorylates a variety of substrates. ACPP-VLP possesses lipid phosphatase activity and inactivates lysophosphatidic acid. ACPP/Prostatic Acid Phosphatase Protein, Mouse (HEK293, His) is the recombinant mouse-derived ACPP/Prostatic Acid Phosphatase protein, expressed by HEK293 , with C-His labeled tag. The total length of ACPP/Prostatic Acid Phosphatase Protein, Mouse (HEK293, His) is 350 a.a., with molecular weight of 44-55 kDa.

HY-P76556

	PTPMT1 Protein, Human (His) Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; PTPMT1; MOSP; PLIP	Human	E. coli
	The PTPMT1 protein is a lipid phosphatase that critically regulates cellular lipid metabolism by dephosphorylating phosphatidylglycerolphosphate (PGP) to form phosphatidylglycerol (PG). This step is critical for the biosynthesis of cardiolipin, a key mitochondrial phospholipid that regulates membrane integrity and mitochondrial activity. PTPMT1 Protein, Human (His) is the recombinant human-derived PTPMT1 protein, expressed by E. coli , with N-His labeled tag. The total length of PTPMT1 Protein, Human (His) is 174 a.a., with molecular weight of ~22 kDa.

HY-P700619

	*Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His)* ACP-3; ACPP; Prostatic Acid phosphatase; PAPf39; PAP	Human	HEK293
	Prostatic acid phosphatase (ACPP) operates as a versatile tyrosine phosphatase under acidic conditions (pH 4-6), dephosphorylating various substrates, including orthophosphate monoesters. With lipid phosphatase activity, ACPP inactivates lysophosphatidic acid in seminal plasma. In prostate cancer, it acts as a tumor suppressor by dephosphorylating ERBB2, deactivating MAPK signaling, and controlling cancer-related processes. ACPP also exhibits ecto-5'-nucleotidase activity in dorsal root ganglion neurons, suggesting a role in pain modulation by generating adenosine from AMP. Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His) is the recombinant human-derived Prostatic acid Phosphatase/ACPP protein, expressed by HEK293, with C-His, GFP labeled tag. The total length of Prostatic acid Phosphatase/ACPP Protein, Human (HEK293, GFP-His) is 350 a.a., with molecular weight of 70.6 kDa.

HY-P701970

	PTPRG Protein, Human PTPRG; Receptor-type tyrosine-protein phosphatase gamma; Protein-tyrosine phosphatase gamma; R-PTP-gamma	Human	E. coli
	PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human is the recombinant human-derived PTPRG protein, expressed by E. coli , with tag free. The total length of PTPRG Protein, Human is 311 a.a., .

HY-P71141

	SHP-1 Protein, Human (His) Tyrosine-Protein phosphatase Non-Receptor Type 6; Hematopoietic Cell Protein-Tyrosine phosphatase; Protein-Tyrosine phosphatase 1C; PTP-1C; Protein-Tyrosine phosphatase SHP-1; SH-PTP1; PTPN6; HCP; PTP1C	Human	E. coli
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Human (His) is the recombinant human-derived SHP-1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of SHP-1 Protein, Human (His) is 299 a.a., with molecular weight of ~33.0 kDa.

HY-P701971

	PTPRG Protein, Human (His) PTPRG; Receptor-type tyrosine-protein phosphatase gamma; Protein-tyrosine phosphatase gamma; R-PTP-gamma	Human	E. coli
	PTPRG protein, also known as G-type protein tyrosine phosphatase receptor, is characterized by its tyrosine phosphatase activity. As a member of the protein tyrosine phosphatase (PTP) family, PTPRG is involved in the dephosphorylation of tyrosine residues in target proteins. PTPRG Protein, Human (His) is the recombinant human-derived PTPRG protein, expressed by E. coli , with N-6*His labeled tag. The total length of PTPRG Protein, Human (His) is 311 a.a., .

HY-P7817

	*Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution)* rHuProstatic acid phosphatase/ACPP, His; Prostatic Acid phosphatase; PAP; 5'-Nucleotidase; 5'-NT, Ecto-5'-Nucleotidase; Thiamine Monophosphatase; TMPase; ACPP	Human	HEK293
	PPAP protein, a nonspecific tyrosine phosphatase, has anticancer and antiproliferative activities. The PPAP protein dephosphorylates a variety of substrates under acidic conditions (pH 4-6), resulting in the inactivation of lysophosphatidic acid in seminal plasma. The PPAP protein is also a common biomarker for prostate cancer and can inhibit tumor development. Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) is the recombinant human-derived Prostatic acid phosphatase/ACPP protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Prostatic acid phosphatase/ACPP Protein, Human (354a.a, HEK293, His, solution) is 354 a.a., with molecular weight of ~50.0 kDa.

HY-P71579

	*TFIIF-associating CTD phosphatase* Protein, Mouse (Myc, His)** Ctdp1; Fcp1; RNA polymerase II subunit A C-terminal domain phosphatase; EC 3.1.3.16; TFIIF-associating CTD phosphatase	Mouse	E. coli
	The TFIIF-related CTD phosphatase protein plays a key role in promoting RNA polymerase II activity by dephosphorylating "Ser-2" and "Ser-5" residues. This enhances the function of RNA polymerase II, allowing the protein to participate in the transcription process. TFIIF-associating CTD phosphatase Protein, Mouse (Myc, His) is the recombinant mouse-derived TFIIF-associating CTD phosphatase protein, expressed by E. coli , with N-His, C-Myc labeled tag. The total length of TFIIF-associating CTD phosphatase Protein, Mouse (Myc, His) is 164 a.a., with molecular weight of ~24.0 kDa.

HY-P76307

	DUSP14 Protein, Human (His-MBP) Dual specificity protein phosphatase 14; MKP-L; MKP-6; DUSP14	Human	E. coli
	DUSP14 protein can inactivate MAP kinase and dephosphorylate ERK, JNK and p38 MAP kinase. Its negative regulation extends to TCR signaling, where DUSP14 dephosphorylates the MAP3K7 adapter TAB1, resulting in inactivation. DUSP14 Protein, Human (His-MBP) is the recombinant human-derived DUSP14 protein, expressed by E. coli , with N-His, N-MBP labeled tag. The total length of DUSP14 Protein, Human (His-MBP) is 191 a.a., with molecular weight of ~60 KDa.

HY-P70870

	MDP1 Protein, Human (HEK293, His) Magnesium-dependent phosphatase 1; MDP-1; EC=3.1.3.48;	Human	HEK293
	MDP1 Protein, a magnesium-dependent phosphatase, potentially functions as a tyrosine phosphatase. MDP1 Protein, Human (HEK293, His) is the recombinant human-derived MDP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MDP1 Protein, Human (HEK293, His) is 176 a.a., with molecular weight of ~18.0 kDa.

HY-P700620

	*Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His)* ACP-3; ACPP; Prostatic Acid phosphatase; PAPf39; PAP	Human	HEK293
	Prostatic acid phosphatase (ACPP) operates as a versatile tyrosine phosphatase under acidic conditions (pH 4-6), dephosphorylating various substrates, including orthophosphate monoesters. With lipid phosphatase activity, ACPP inactivates lysophosphatidic acid in seminal plasma. In prostate cancer, it acts as a tumor suppressor by dephosphorylating ERBB2, deactivating MAPK signaling, and controlling cancer-related processes. ACPP also exhibits ecto-5'-nucleotidase activity in dorsal root ganglion neurons, suggesting a role in pain modulation by generating adenosine from AMP. Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His) is the recombinant human-derived Prostatic acid Phosphatase/ACPP protein-VLP, expressed by HEK293, with N-10*His labeled tag. The total length of Prostatic acid Phosphatase/ACPP Protein-VLP, Human (386a.a, HEK293, His) is 386 a.a., with molecular weight of 47.5 kDa.

HY-P75322

	CSK Protein, Mouse (sf9) Tyrosine-protein kinase CSK; C-Src kinase; CSK	Mouse	Sf9 insect cells
	CSK protein is a non-receptor tyrosine protein kinase that regulates cell growth, differentiation, migration and immune responses by phosphorylating Src family kinases (SFK) (such as LCK, SRC, HCK, FYN, LYN, CSK or YES1) . This phosphorylation induces SFK to form an inactive conformation, thereby inhibiting signaling by receptors such as T cell receptor (TCR) and B cell receptor (BCR). CSK Protein, Mouse (sf9) is the recombinant mouse-derived CSK protein, expressed by Sf9 insect cells , with tag free. The total length of CSK Protein, Mouse (sf9) is 450 a.a., with molecular weight of ~46 kDa.

HY-P70987

PPP1R1A Protein, Human (His)

Protein phosphatase 1 Regulatory Subunit 1A; Protein phosphatase Inhibitor 1; I-1; IPP-1; PPP1R1A; IPP1
Human E. coli

HY-P70361

	INPP1 Protein, Human (HEK293, His) rHuInositol polyphosphate 1-phosphatase/INPP1, His; Inositol Polyphosphate 1-phosphatase; IPP; IPPase; INPP1	Human	HEK293
	INPP1 protein, also known as inositol polyphosphate-1-phosphatase, is a phosphatase that plays a crucial role in inositol phosphate metabolism. The activity of this protein depends on magnesium ions and is responsible for catalyzing the hydrolysis of the phosphate group at position 1 of inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. INPP1 Protein, Human (HEK293, His) is the recombinant human-derived INPP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of INPP1 Protein, Human (HEK293, His) is 399 a.a., with molecular weight of 40-50 kDa.

Cat. No.	Product Name	Application	Reactivity

HY-P81348

PHLPP2 Antibody (YA1093) PHLPP2; KIAA0931, PHLPPL; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like (PHLPP-like)	IHC-P	Human

HY-P82537

BLNK Antibody (YA2282) BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa	WB, IP	Human, Mouse, Rat

HY-P83492

MLK3 Antibody (YA3237) MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase	WB, ICC/IF	Human

HY-P82911

Phospho-Src (Tyr530) Antibody (YA2656)

Src; Src1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-Src; p60-Src
WB, IP Rat

HY-P80338

Src Antibody	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
Src Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 60 kDa, targeting to Src. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80339

SRC1 Antibody	WB, IHC-P, IP	Human
SRC1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 157 kDa, targeting to SRC1. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human.

HY-P82649

SHC Antibody (YA2394) SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

HY-P81323

PP1C gamma Antibody (YA1068) PP 1G; PP-1G; PP1G; PP1G_HUMAN; PP1gamma; PPP 1G; PPP1CC; PPP1CC protein; PPP1G; Protein phosphatase 1 catalytic subunit gamma isoform; Protein phosphatase 1C catalytic subunit; Protein phosphatase 1C subunit; Protein phosphatase 2C gamma isoform; Serine/threonine phosphatase 1 gamma; Serine/threonine protein phosphatase PP1 gamma catalytic subunit; Serine/threonine-protein phosphatase PP1-gamma catalytic subunit.	WB	Human

HY-P81898

SHP2 Antibody (YA1643) PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	WB, IHC-P, IP	Human

HY-P81304

Placental Alkaline Phosphatase Antibody (YA1038)

ALPP; PLAP; Alkaline phosphatase; placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1
WB Human
HY-P81304A

Placental Alkaline Phosphatase Antibody (YA1039)

ALPP; PLAP; Alkaline phosphatase; placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1
WB Human

HY-P81305

PP1C alpha Antibody (YA1040) Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein phosphatase 2C Alpha Isoform; Serine threonine protein phosphatase PP1 alpha catalytic subunit; Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.	WB, IHC-F, IHC-P, ICC/IF	Human

HY-P81305A

PP1C alpha Antibody (YA1041) Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein phosphatase 2C Alpha Isoform; Serine threonine protein phosphatase PP1 alpha catalytic subunit; Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.	WB, ICC/IF	Human

HY-P80514

*Phospho-Src* (Tyr419) Antibody**	WB, FC	Human
Phospho-Src (Tyr419) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 60 kDa, targeting to Phospho-Src(Y419). It can be used for WB,FC assays with tag free, in the background of Human.

HY-P81955

PP1C alpha/beta Antibody (YA1700) Alpha isoform serine threonine protein phosphatase PP1alpha 1 catalytic subunit; Catalytic subunit; PP1A; PP1A_HUMAN; PP1alpha; PP2C ALPHA; PP2CA; Ppp1ca; Protein phosphatase 2C Alpha Isoform; Serine threonine protein phosphatase PP1 alpha catalytic subunit; Serine threonine protein phosphatase PP1 alpha catalytic subunit protein phosphatase 1; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit.	WB, IHC-P, IP	Human, Mouse, Rat

HY-P80645

DUSP1 Antibody DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; Mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; Protein-tyrosine phosphatase CL100	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
DUSP1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to DUSP1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80012

*Alkaline Phosphatase* Antibody**	WB, ICC, IHC-P, IP, FC	Human, Mouse
Alkaline Phosphatase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 57 kDa, targeting to Alkaline Phosphatase. It can be used for WB,ICC,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse.

HY-P81948

PP2A alpha/beta Antibody (YA1693) PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat, Hamster

HY-P82763

Calcineurin A Antibody (YA2508) PPP3CA; CALNA; CNA; Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform	WB, ICC/IF, FC	Human, Mouse, Rat

HY-P83111

Phospho-PP2A alpha (Tyr307) Antibody (YA2856) PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat

HY-P81324

PPP5C Antibody (YA1069) FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; PPP5; PPP5_HUMAN; PPP5C; PPT; Protein phosphatase 5; catalytic subunit; Protein phosphatase T; Serine/threonine protein phosphatase 5; Serine/threonine-protein phosphatase 5.	WB	Human

HY-P83087

SHIP1 Antibody (YA2832) INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1	WB, IHC-P, IP, FC	Human

HY-P82879

CDC25C Antibody (YA2624)

CDC25C; M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C
WB, IHC-P, ICC/IF, IP, FC Human

HY-P80646

DUSP3 Antibody Dual specificity protein phosphatase VHR; VHR; Vaccinia H1-related phosphatase	WB, IHC-F, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat
DUSP3 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 20 kDa, targeting to DUSP3. It can be used for WB,IHC-F,IHC-P,ICC/IF,FC,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P83344

Phospho-SHIP1 (Tyr1020) Antibody (YA3089) INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1	WB, ICC/IF, IP	Human

HY-P81990

KAT13A Antibody (YA1735)

bHLHe74; mNRC 1; NCoA 1; RIP160; Src 1
WB, IHC-P, IP Human
HY-P81961

Prostatic Acid Phosphatase Antibody (YA1706)

5' -NT; 5' -nucleotidase; ACP3; PAP; Prostatic acid phosphatase; TMPase
WB, IHC-P, ICC/IF, IP Human

HY-P81307

SHP1 Antibody (YA1044) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IP	Human

HY-P81307A

SHP1 Antibody (YA1045) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IHC-P	Human

HY-P81491

INPP4B Antibody (YA1236) 4-bisphosphate 4-phosphatase; Inositol polyphosphate 4 phosphatase type II 105kDa; Inositol polyphosphate 4-phosphatase type II; Inpp4b; MGC132014; Type II inositol 3; 4 bisphosphate 4 phosphatase; Type II inositol-3	IHC-P	Human

HY-P82535

DUSP6 Antibody (YA2280)

HH19; MKP3; PYST1; DUSP6; DUSP6a; Dual specificity phosphatase 6
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat
HY-P81814

Intestinal Alkaline Phosphatase Antibody (YA1559)

Alpi; Glycerophosphatase; IAP
WB, IHC-P Human
HY-P81953

PPM1G Antibody (YA1698)

Protein phosphatase 1G; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma
WB Human, Mouse, Rat
HY-P82997

CSK Antibody (YA2742)

CSK; Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL
WB, IHC-P Human, Mouse, Rat
HY-P82031

PTP1B Antibody (YA1776)

PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B
WB, IHC-F, IHC-P, ICC/IF Human
HY-P82899

DARPP32 Antibody (YA2644)

PPP1R1B; DARPP32; Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein
WB, IHC-P, IP Human, Mouse, Rat
HY-P81300

Phospho-PTP1B (Ser352) Antibody (YA1027)

PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B
WB, ICC/IF, IP Human
HY-P81300A

Phospho-PTP1B (Ser378) Antibody (YA1028)

PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B
WB, IHC-P Human
HY-P83364

PPP1R1A Antibody (YA3109)

I 1; I1; Inhibitor 1; IPP1; Ppp1r1a; Protein phosphatase 1 regulatory (inhibitor) subunit 1A
WB, IHC-P, ICC/IF, IP, FC Human, Mouse, Rat

HY-P80681

FYN Antibody FYN; Tyrosine-protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn	WB	Human, Mouse, Rat
FYN Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 61 kDa, targeting to FYN. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80816

Phospho-FAK (Tyr576) Antibody PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK	WB	Human, Mouse
Phospho-FAK (Tyr576) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 119 kDa, targeting to Phospho-FAK (Tyr576). It can be used for WB assays with tag free, in the background of Human, Mouse.

HY-P80603

CD45 Antibody (YA800) PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45	WB, IHC-P	Human, Mouse
CD45 Antibody (YA800) is a non-conjugated and Mouse origined monoclonal antibody about 147 kDa, targeting to CD45. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.

HY-P81958

PP1C beta Antibody (YA1703)

PPP1CB; Serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CD
WB, IHC-F, IHC-P, ICC/IF, IP Human, Mouse, Rat

HY-P83327

WAVE 2 Antibody (YA3072) WASF2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2	WB, IHC-P	Human, Mouse, Rat

HY-P80743

Lck Antibody (YA712) LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK	WB	Human
Lck Antibody (YA712) is a non-conjugated and Mouse origined monoclonal antibody about 58 kDa, targeting to Lck (3E5). It can be used for WB assays with tag free, in the background of Human.

HY-P83448

PTP4A2 Antibody (YA3193)

protein tyrosine phosphatase type IVA; member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b
WB, IP Human

HY-P80905

SUMO1 Antibody (YA047) SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein	WB, IHC-P	Human, Mouse, Rat
SUMO1 Antibody (YA047) is a non-conjugated and Rabbit origined monoclonal antibody, targeting to SUMO1. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P81233

DDIT3 Antibody GADD153; CHOP; Growth arrest and DNA damage-inducible 153; C/EBP homologous protein; C/EBP homology Protein; CEBPZ; CHOP10; DDIT 3; DNA Damage Inducible Transcript 3; GADD 153; Growth Arrest and DNA Damage Inducible Protein 153; Growth arrest and DNA damage inducible protein GADD153; MGC4154; DDIT3_HUMAN.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep)
DDIT3 Antibody is an unconjugated, approximately 19 kDa, rabbit-derived, anti-DDIT3 polyclonal antibody. DDIT3 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, rabbit, sheep background without labeling.

HY-P81616

SIRP alpha Antibody (YA1361) SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibito	FC, ELISA	Human

HY-P80785

PGP9.5 Antibody UCHL1 / PGP9.5; UCHL1; B220; CD 45; CD45; cd45 antigen; ec3.1.3.48; GP 180; GP180; Human homolog of severe combined immunodeficiency due to PTPRC deficiency; L CA; L-CA; lca; Leukocyte common antigen; LY 5; LY5; Protein tyrosine phosphatase receptor type	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
PGP9.5 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to PGP9.5. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

Cat. No.	Product Name		Classification

HY-135699

TD52 1 Publications Verification		Alkynes
TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity . TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135699A

TD52 dihydrochloride 1 Publications Verification		Alkynes
TD52 dihydrochloride, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 dihydrochloride mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 dihydrochloride indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 dihydrochloride has less p-EGFR inhibition and has potent anti-cancer activity . TD52 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130913

5-FAM-Alkyne		Alkynes
5-FAM-Alkyne is a high selective and sensitive fluorescent biosensor for alkaline phosphatase (ALP) . 5-FAM-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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